A Review Of ceesdekker

2009, discovery of a fresh phenotype for bacteria in slim nanofluidic slits; and 1st detection of community protein buildings alongside DNA working with good-point out nanopores

Human Rad51 filaments on double- and solitary-stranded DNA: correlating regular and irregular kinds with recombination functionality.

For a human being, I possess the biblical assignment to check out and use all the things in creation for the advantage of my neighbour. I tend not to encounter any conflict among religion and science. Quite the opposite, my religion stimulates me to do science, to become open-minded on the earth.’

Sculpting nano-electrodes using a transmission electron beam for electrical and geometrical characterization of nanoparticles.

Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond clever layout in 2005. (nl)

Electrical transport in monolayers of phthalocyanine molecular wires and AFM imaging of a single wire bridging two electrodes

We use nanofabricated microfluidic structures to pattern spatial boundaries for germs and biomimetic vesicles with reconstituted protein networks and this assess the basic purpose of spatial confinement within the molecular and mobile level. Our projects consist of the next:

Move-pushed rotary motors including windmills and drinking water wheels push useful procedures in human Modern society. Although examples of this kind of rotary motors also characteristic prominently in cell biology, their synthetic development for the nanoscale has remained hard. Here we show move-pushed rotary motion of the self-arranged DNA nanostructure that is certainly docked on to a nanopore in a skinny solid-condition membrane. An elastic DNA bundle self-assembles right into a chiral conformation upon phoretic docking on to the reliable-point out nanopore, and subsequently shows a sustained unidirectional rotary motion of up to 20 rev s−1.

Knowing basic processes regulating the spatial and dynamic organisation in the DNA in Reside cells.

It was throughout this period that Dekker carried out analysis on magnetic spin programs and on sound in superconductors and semiconductors.

Because 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of https://www.ceesdekker.net DNA loop extrusion and supercoiling to DNA translocation by nanopores. A lot more a short while ago his investigation has focused on finding out chromatin composition and cell division with microbes on chip, although he is also aiming to ultimately Create artificial cells from the bottom up.

2006, initial demonstration of molecular sorting in a lab with a chip working with biomotors; discovery of nanobubbles in reliable-state nanopores; and first estimate of electrokinetic Electricity conversion in the nanofluidic channel

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Illustration (two) of bending configurations in 3D simulations of DNA rods on nanopores. A portion of the membrane is shown in grey, the rim in the pore is highlighted in crimson, plus a 3D rendering with the movement of your DNA rod is displayed.