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It absolutely was only within the nineties though, when nanotechnology experienced advanced into a amount in which one molecules might be manipulated, that the 1st experimental devices started to look.

The subsequent articles are merged in Scholar. Their mixed citations are counted just for the very first write-up.

Sculpting nano-electrodes having a transmission electron beam for electrical and geometrical characterization of nanoparticles.

2015, discovery that condensin is often a hugely flexible protein composition; and 1st detection of DNA knots making use of nanopores

Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.

‘At the beginning we looked at biological units using a physical watch and acted on the basis in the applications we understood. It took a few years in advance of we started Operating more on the massive biological concerns. I then started to get in touch with it nanobiology, a time period that didn't exist at the time.

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In 1993, like a youthful and keen associate professor at Delft University of Technological know-how, I had originally concentrated the research attempts of my team on measuring the electrical conductance of only one conducting-polymer molecule. Inside two a long time, we experienced established a device in which just one wire of a phthalocyaninepolysiloxane polymer was connected amongst two intently spaced steel nanoelectrodes.

It was throughout this period that Dekker performed exploration on magnetic spin devices and on sound in superconductors and semiconductors.

[14] In 2005 Dekker grew to become linked to Netherlands-wide discussions about Smart Style and design, a motion that he has because Obviously distanced himself from. Dekker advocates that science and faith aren't in opposition but may be harmonized.

Cees Dekker is Distinguished University Professor ceesdekker.net at TU Delft. Trained for a physicist, he pioneered nanotechnology with numerous discoveries on carbon nanotubes in the nineties. Because 2000, he moved to one-molecule biophysics and nanobiology. His existing investigate focuses on (i) nanopores for protein sequencing; (ii) chromosome composition, particularly SMC motor protein; and (iii) building a residing artificial cell from lifeless molecules. Dekker can be an elected member with the KNAW and fellow towards the APS as well as IOP.

Allow’s 1st seem back in the mean time if you chose to change your aim from superconductivity and nanotubes to biology at the conclusion of the 1990s.

Stable-condition nanopores have confirmed to be a shockingly functional probe for solitary-molecule analysis of DNA. I'll describe some of our the latest results – particularly DNA knots – and our initiatives to increase the capabilities of stable-state nanopores even further, from the course of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.